Home > Academics > Academic Units > Departments > Computer Science and Engineering > Pralay Mitra
Ph.D., Indian Institute of Science, Bangalore
Associate Professor
Computer Science and Engineering
We are interested in realizing the biological phenomenon thourgh computational and experimental techniques. The focus is on developing new computational algorithms and tools for biological and clinical investigators. Protein Interaction Modeling: The correct biological association of a protein molecule with another is the key to understand the function of a protein complex. We aim to develop efficient and effective computational methods to predict protein interaction as an alternative of experimental methods like X-Ray crystallography or NMR. Protein Interaction Network: Designing or modeling the function of a protein at the macromolecular level is incomplete without a wholistic view of the total interaction map. Representing a protein as a vertex and their interaction as an edge of the graph we develop methods to infer the role of a protein from global perspective. Protein Design and stability analysis: The design and engineering of proteins is readily transforming our lives to include new medicines and opens new avenues in industrial research. We aspire to develop protein design tools that could probe for the novel protein sequences with altered binding affinity.
A Network-based Zoning for Parallel Whole-Cell Simulation by Das B., Patil A. R., Mitra P. Bioinformatics 35 88-94 (2019)
Analyzing change in protein stability associated with Single Point Deletions in a newly defined protein structure database by Banerjee A., Levy Y. , Mitra P. Journal of Proteome Research 18 1402-1410 (2019)
An evolution-based approach to de novo protein design and case study on Mycobacterium Tuberculosis by Mitra P., Shultis D. , Brender J. R., Czajka J. , Marsh D. , Gray F. , Cierpicki T. , Zhang Y. PLoS Computational Biology 9 e1003298- (2013)
Combining Bayes classification and point group symmetry under Boolean framework for enhanced protein quaternary structure inference by Mitra P., Pal D. Structure 19 304-312 (2011)
EvoDesign: de novo protein design based on structural and evolutionary profiles by Mitra P., Shultis D. , Zhang Y. Nucleic Acids Research 41 W273-W280 (2013)
Using correlated parameters for improved ranking of protein-protein docking decoys by Mitra P., Pal D. Journal of Computational Chemistry 32 787-796 (2011)
New measures for estimating surface complementarity and packing at protein-protein interfaces by Mitra P., Pal D. FEBS Letters 584 1163-1168 (2010)
How many protein-protein interaction types exist in nature? by Garma L., Mukherjee S. , Mitra P. , Zhang Y. PLoS One 7 e389- (2012)
Changing the Apoptosis Pathway through Evolutionary Protein Design by Shultis D., Mitra P. , .. .. , Wang S. , Zhang Y. Journal of Molecular Biology 431 825-841 (2019)
PRUNE and PROBE two modular web services for protein-protein docking by Mitra P., Pal D. Nucleic Acids Research 39 229-234 (2011)
Designer Therapeutic Elucidation of Novel Small Molecular Inhibitor Targeting ETV6-NTRK3 Associated Gene Fusion in Glioblastoma Indian Council of Medical Research, Dept. of Health Research, Ministry of Health and Family Welfare
Design & Development of IIT Kharagpur Website IIT KHARAGPUR
Anupam Banerjee
Area of Research: Bioinformatics
Barnali Das
Area of Research: Bioinformatics
Abantika Pal
Area of Research: Bioinformatics
Angana Biswas
Area of Research: Cancer Biology
Shubhrangshu Ghosh
Area of Research: Bioinformatics
