Home > Academics > Academic Units > Departments > Chemistry > Swagata Dasgupta
Professor
Chemistry
Protein aggregation studies: Work with polyphenols and surfactants on the fibrillation of proteins to study amyloid fibrils. Aggregation studies involve human serum albumin, lysozyme and the amyloid peptide fragment Aβ25-35. Effects of a static electric field on the disruption of fibrils have also been reported.
Studies with the eye lens proteins: Modified γ- crystallin (HGCc) from the discarded cataractous emulsion of patients has been isolated and characterized. The major polyphenol in green tea, EGCG was found to prevent tryptophan oxidation of cataractous ocular lens human γ-crystallin in presence of H2O2. The discarded mass is being used to prepare protein nanoparticles and films for applications in drug delivery, wound healing etc. with a patent filed for the same.
Protein ligand binding: Natural and synthetic inhibitors of Ribonuclease A and angiogenin are being developed. Studies with ribonucleases such as angiogenin indicated that the process of angiogenesis, the capacity to form blood vessels, was inhibited by polyphenols present in green tea.
Scheme for Promotion of Academic and Research Collaboration (SPARC) - IIT Kharagpur as a Nodal Institute MHRD
Scheme for Promotion of Academic and Research Collaboration (SPARC) - Projects of IIT-KGP MHRD
Poly Lactic-Co-Glycolic Acid (PLGA) Based Nanoparticles for Delivery of Polyphenols and Effect of Human Serum Albumin (HSA) on their Release Property and Antioxidant Property Council of Scientific and Industrial Research, Extramural Research Division
Scheme for Promotion of Academic and Research Collaboration (SPARC) MHRD
Femtosecond laser facility to investigate confined media, biological assemblies. room temperature ionic liquids and nano-materials Science and Engineering Research Board (SERB)
Direct-To-Home (DTH) SWAYAM Prabha MHRD, Department of Higher Education, NMEICT, New Delhi
Centre of excellence for training and research in Microfluidics IIT KHARAGPUR
Anupam Apoorva
Area of Research: Secondary metabolites research
Pritam Roy
Area of Research: Protein Chemistry
Sultana Parveen
Area of Research: Protein isolation and characterization
Ashrukana Das
Area of Research: Inhibition of ribonucleases with synthetic carbohydrates
Pampa Mondal
Area of Research: Inhibition of ribonucleases with synthetic nucleosides
Atashi Panda
Area of Research: Protein Chemistry
Anang Kumar Singh
Area of Research: Nano-Bio Science
Hemant Kumar Srivastava
Area of Research: Neurobiology
Prasun Chowdhury
Area of Research: Protein Chemistry
Krishna Halder
Area of Research: Protein Chemistry
Sreshtha Chaki
Area of Research: Protein Chemistry
