Home > Academics > Academic Units > Schools > School of Medical Science and Technology > Mahitosh Mandal
Professor
School of Medical Science and Technology
Dr. Mahitosh Mandal has made outstanding contribution in cancer research. He has identified specific genes and their biological functions in various cancers. In USA Lab., he has cloned Metastasis Associated gene 1 with ER-binding motif which stimulates malignant phenotypes. Also he discovered a link between telomerase activity and cancer progression. While at IIT, Kharagpur, he established a new Division of Cancer Biology where he has made significant contribution in developing newer targets for treatment and prevention of cancer. He showed that incorporation of an anti-EGFR molecule with VEGFR for chemotherapy can be more effective in treating patients with locally advanced or metastatic breast cancer. Mahitosh has also shown that Diacerein, an IL-6 inhibitor offered a novel blueprint for cancer therapy by hampering IL-6 /STAT3/MAPK/Akt network but without any toxic effects. Presently, he is engaged in nanoparticle mediated drug delivery and has shown that celecoxib-loaded Hap- Cht nanoparticles in colon cancer can serve as an effective and safe means of delivering the drug. Currently, he along with a team of oncologist, physicist and engineers are trying to determine specific molecular, bio-physical and bio-electrical changes in cancer cells during malignant transformation and acquisition of chemo-radioresistance. An outstanding contribution of Dr. Mandal as evidenced by majority of his publications in high impact factor Scopus indexed journals.
Nano-platform Based Carboplatin Delivery in Retinoblastoma by Modulating Blood Retinal Barrier Council of Scientific and Industrial Research, Extramural Research Division
Engineered Nano Hydrogel for Target Specific Delivery in Squamous Cell Carcinoma Apex Committee of SPARC
System for Cyto - Reduction of Circulating Cancer Cells from Blood and a Method Thereof Alacris Research and Development Private Limited
Customized Bioactive Porous Titanium Implants with Improved Tissue-integration and Attenuated Aseptic Loosening for Orthopaedic Applications Life Sciences Research Board
Photoresponsive Nanoconjugates for Efficient Combination Chemotherapy : Sequential and Cocktail Approaches Science and Engineering Research Board (SERB)
Synthesis, Solution Properties and In Vitro Evaluation of Stimuli-Responsive Polymer-Based Prodrug Systems Science and Engineering Research Board (SERB)
Payel Banik
Area of Research: Cancer Biology
Subhayan Das
Area of Research: Cancer Biology
Bikash Chandra Jena
Area of Research: Cancer Biology
Deblina Bharadwaj
Area of Research: Cancer Biology
Angana Biswas
Area of Research: Cancer Biology
Moumita Kundu
Area of Research: Cancer Biology
Ranabir Majumder
Area of Research: Validation of phytomedicine on chronic disease therapy
Pritam Kumar Roy
Area of Research: Cancer Biology
Shreya Banerjee
Area of Research: Cancer Biology
