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Swagata Das Gupta

	S Dasgupta Ph.D.(RPI New York) Associate Professor, Chemistry Warden, Mother Teresa Hall
	S Dasgupta joined the Institute in 1995

Contact Addresses

Residence	B-199, IIT Campus, Kharagpur 721302
Phone (office)	+91 - 3222 - 283306
Phone (residence)	+91 - 3222 - 283923 (IIT Phone) +91 - 3222 - 277780 (Private Phone)
email	swagata @ chem.iitkgp.ernet.in
More Information

Research Areas

Protein Chemistry; Protein Ligand binding

Member of Professional Bodies

Life Member : Chemical Research Society of India

Publications: 2009 - 2010

Lipase mediated isoamyl acetate synthesis in solvent-free system using vinyl acetate as acyl donor. by Kumari, A., Mahapatra, P., Garlapati, V. K., Banerjee, R., Dasgupta, S. Food Technol. Biotechnol., 47, 13-18. (2009)
Molecular Interactions of Isoxazolcurcumin with Human serum albumin: Spectroscopic and Molecular Modeling Studies. by Sahoo, B.K., Ghosh, K.S. Bera, R. and Dasgupta S. Biopolymers, 91, 108-119. (2009)
Morpholino, Piperidino, and Pyrrolidino Derivatives of Pyrimidine Nucleosides as Inhibitors of Ribonuclease A: Synthesis, Biochemical, and Crystallographic Evaluation. by Samanta A., Leonidas D.D. Dasgupta S., Pathak, T., Zographos, S.E. and Oikonomakos, N.G. J. Med. Chem., 52, 932-942. (2009)
An investigation of the molecular interactions of diacetylcurcumin with Ribonuclease A. by Sahoo, B.K., Ghosh, K.S. and Dasgupta S. Prot. Pept. Letters, 12, 1485-1495. (2009)
Inhibition of Ribonuclease A by Nucleoside-dibasic acid conjugates. by Debnath J., Dasgupta S. and Pathak, T. Bioorg. Med. Chem., 17, 6491-6495. (2009)
Nucleoside-amino acid conjugates: An alternative route to the design of Ribonuclease A inhibitors. by Debnath J., Dasgupta S. and Pathak, T. Bioorg. Med. Chem., 17, 4921-4927. (2009)
Flexible structural protein alignment by a sequence of local transformations. by Rocha, J., Segura, J., Wilson, R. C., Dasgupta, S. Bioinformatics, 25, 1625-1631. (2009)
Chemistry is evergreen: 2008 Nobel Prize in chemistry. by Dasgupta,S. Resonance, 14, 248-258. (2009)
A spectroscopic investigation into the interactions of 3´-O-carboxy esters of thymidine with Bovine Serum Albumin. by Ghosh, K.S., Sen, S., Sahoo, B.K. and Dasgupta, S. Biopolymers, 91, 737-744. (2009)
Design and Synthesis of Enediyne-peptide Conjugates and Their Inhibiting Activity Against Chymotrypsin. by Datta, S., Basak A. and Dasgupta, S. Bioorg. Med. Chem, 17, 3900-3908. (2009)

Publications: 2008 - 2009

Studies on the interaction of diacetylcurcumin with calf thymus-DNA. by Sahoo, B.K., Ghosh, K.S. Bera, R. and Dasgupta S. Chem. Phys., 351,163-169. (2008)
Studies on the interaction of copper complexes of (−)-epicatechin gallate and (−)-epigallocatechin gallate with calf thymus DNA. by Ghosh K.S., Debnath J., Dutta P., Sahoo B.K. and Dasgupta S. J. Inorg. Biochem.,, 102, 1711-1718. (2008)
Design, Synthesis and RNase A Inhibition Activity of Catechin and Epicatechin and Nucleobase Chimeric Molecules. by Roy, B., Datta, S., Chowdhury, A., Basak A. and Dasgupta, S. Bioorg. Med. Chem. Lett., 18, 5411-5414. (2008)
Using Proton Nuclear Magnetic Resonance to study the mode of Ribonuclease A inhibition by competitive and noncompetitive inhibitors. by Ghosh K.S., Debnath J., Pathak, T. and Dasgupta S. Bioorg. Med. Chem. Lett., 18, 5503-5506. (0)
Fluorescence, Anisotropy and Docking Studies of Proteins through Excited State Intramolecular Proton Transfer Probe Molecules by Maity S. S., Samanta S., Sardar, P. S., Pal, A., Dasgupta S. and Ghosh, S. Chem. Phys., 354, 162-173. (2008)

Publications: 2007 - 2008

Prediction based protein engineering of domain I of Cry2A entomocidal toxin of Bacillus thuringiensis resulted enhancement of toxicity against lepidopteran insects. by Mandal, C.C., Gayen, S., Basu, A., Ghosh, K.S., Dasgupta, S., Maiti, M.K., Sen, S.K., Prot. Engg. Des. Sel., 20, 599-606 (2007)
Inhibition of Ribonuclease A by polyphenols present in green tea by Ghosh, K.S., Maiti, T.K., Debnath, J. and Dasgupta S., Proteins: Structure, Function and Bioinformatics, 69, 566-580 (2007)
Studies on the interaction of isoxazolcurcumin with calf thymus DNA. by Bera, R., Sahoo, B.K., Ghosh, K.S. and Dasgupta S., Intl. J. Biol. Macromol., 42, 14-21 (2008)
Investigating the binding of curcumin derivatives to bovine serum albumin by Sahoo, B.K., Ghosh, K.S. and Dasgupta S., Biophysical Chemistry, 132, 81-88 (2008)
Photoinduced Electron Transfer between Hen Egg White Lysozyme and anticancer drug menadione by Banerjee S., Dutta Choudhury S., Dasgupta S. and Basu S., J. Luminescence, 128, 437-444. (2008)
The interaction of Silibinin with Human serum albumin: A spectroscopic investigation by Maiti, T.K., Ghosh, K.S., Samanta A. and Dasgupta S., J. Photochem. Photobiol. A: Chemistry, 194, 297-307. (2008)
Spectrophotometric studies on the interaction between (-)-Epigallocatechin gallate and Lysozyme. by Ghosh, K.S., Sahoo, B.K., and Dasgupta S., Chem. Phys. Lett., 452, 193-197. (2008)
Energy Transfer Photophysics from Serum Albumins to Sequestered 3-Hydroxy-2-Naphthoic Acid, an Excited State Intramolecular Proton Transfer Probe. by Sardar, P. S., Samanta S., Maity S. S., Dasgupta S. and Ghosh, S., J. Phys. Chem. B, 112, 3451 - 3461. (2008)
Exploring the potential of 3'-O-carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin. by Ghosh K.S., Debnath J., Dutta P., Sahoo B.K., Dasgupta S., Bioorg Med Chem., 16, 2819-2828. (2008)

Publications: 2006 - 2007

Characterization of the Tryptophan Residues of Human Placental Ribonuclease Inhibitor and its Complex with Bovine Pancreatic Ribonuclease A by Steady State and Time Resolved Emission Spectroscopy. by Sardar, P. S., Maity S. S., Ghosh, S., Chatterjee, J., Maiti, T.K. and Dasgupta S., J. Phys. Chem. B, 110, 21349-21356 (2006)
pH dependent surface enhanced Raman study of Phe + Ag Complex and DFT calculations for spectral analysis. by Ojha, A.K., Singha, A., Dasgupta, S., Singh and Roy, A., Chem. Phys. Lett, 431, 121-126. (2006)
Copper complexes of (-)-Epicatechin gallate and (-)-Epigallocatechin gallate act as inhibitors of Ribonuclease A. by Ghosh, K.S., Maiti, T.K., Mandal A. and Dasgupta S., FEBS Lett., 580, 4703-4708. (2006)
Isolation and partial characterization of Ribonuclease Inhibitor from goat liver by Chatterjee, J., Maiti, T.K. and Dasgupta S., Prot. Pept. Letters, 13, 779- 783. (2006)

Publications: 2005 - 2006

A docking interaction study of the effect of critical mutations in Ribonuclease A on protein-ligand binding. by Mukherjee, S., De, S., Ghosh, Z., and Dasgupta, S., Biochem. Mol. Biol. Edu., 33, 335–343. (2005)
Comparison of metal–amino acid interaction in Phe–Ag and Tyr–Ag complexes by spectroscopic measurements. by Singha, A., Dasgupta, S., and Roy, A., Biophysical Chemistry, 120, 215 – 224. (2006)
3'-N-Alkylamino-3'-deoxy-ara-uridines: A new class of potential inhibitors of ribonuclease A and angiogenin. by Maiti, T. K, De, S., Dasgupta, S., and Pathak, T., Bioorg. Med. Chem., 14, 1221–1228. (2006)
Binding of All-trans Retinoic acid to human serum albumin: Fluorescence, FT-IR and Circular dichroism studies. by Maiti, T.K., Ghosh, K.S., Debnath, J., and Dasgupta S., Intl. J. Biol. Macromol., 38, 197-202. (2006)
Interaction of (-)-Epigallocatechin-3-Gallate With Human Serum Albumin: Fluorescence, Fourier Transform Infrared, Circular Dichroism, and Docking Studies by Maiti, T.K., Ghosh, K.S., and Dasgupta S., Proteins, 64, 355-362. (2006)
The binding of 3´-N-piperidine-4-carboxyl-3´-deoxyara- uridine to Ribonuclease A in the crystal. by Leonidas, D. D., Maiti T. K., Samanta A., Dasgupta S. Pathak, T., Zographos S. E., Oikonomakos, N. G., Bioorg. Med. Chem., 14, 6055-6064. (2006)
A study of the interactions of green tea polyphenols with Angiogenin and Ribonuclease A. by Debnath J., Maiti T.K., Ghosh K.S., Chatterjee J., and Dasgupta S, FEBS J. 272,, 272, 368-368 Suppl. (2005)

Publications: 2004 - 2005

Characterization of the Non-regular Regions of Proteins by a Contortion Index. by De, S., Sur, K., and Dasgupta, S., Biopolymers, 79 (2005) 63-73
Green tea polyphenols as inhibitors of ribonuclease A. by Ghosh, K.S., Maiti, T.K., and Dasgupta S., Biochemical and Biophysical Research Communication, 325 (2004) 807-811

Some Earlier Publications

Effect of green tea polyphenols on angiogenesis induced by an angiogenin-like protein by T. K. Maity, J. Chatterjee and S. Dasgupta, Biochem. Biophys. Res. Comm., 308 (2003) 64-67
The Nature of the Turn in Omega Loops of Proteins by M. Pal and S. Dasgupta,, Proteins, 51 (2003) 591-606
Isolation and Characterization of an Angiogenin like protein from goat plasma by T. K. Maity and S. Dasgupta, Protein Pept. Letters, 9 (2002) 283-288
Isolation and Characterization of an Angiogenin like protein from goat plasma by T. K. Maity and S. Dasgupta, Protein Pept. Letters, 9 (2002) 283-288

Indian Institute of Technology Kharagpur, Kharagpur - 721302, INDIA
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