Nano-Bio Research Lab (NBRL)

We, are an interdisciplinary research group, working in translating nanotechnology for biomedical applications. NBRL is a new and developing group of members coming from a variety of backgrounds, including biotechnology, polymer technology, materials science, chemistry, physiology, and pharmacy. NBRL also include collaborative team of academicians, scientists, clinicians, and industry personnel. The following themes is the current focus of NBRL:

Nanomedicine and Drug / Gene Delivery
NBRL will be focussing on taking up the existing challenges in biomedical sector to develop prototypes / products / processes for nano-formulations for different drug / gene delivery. We are aiming on safely and efficiently translating new therapeutic agents from bench to bedside with the goal of improving human health.

Biomaterials and Regenerative Medicine
At the current stage, NBRL is working on engineering nanomaterials for their possible applications in bone, wound, and inflammatory diseases. The interdisciplinary team of academicians, clinicians, industry personnel, and scientists are focussing to solve the challenge in collaboration.

Nanomaterials – Biomolecule Interaction
The nano–bio interactions will not only influence the function and fate of nano-formulations, but also affect the therapeutic behaviour of the formulation. Understanding the behaviour of nano-formulations in biological environment is also a focus of NBRL. NBRL is focussing to evaluate the basic mechanisms of the reactions at nanomaterial–biology (nano–bio) interfaces and find strategies to manipulate the nano–bio reactions for its biomedical applications.

Sustainable Nanotechnology
The additional approach of nano-BILY will be to engineer the nano-formulations for the efficient nutraceuticals with a focus to solve the nutritional deficiency in human health. Safe production and use of nanomaterials require effective risk management. For this purpose, we combine nano-related exposure and toxicity knowledge to develop processes and procedures for risk assessment and management of nanomaterials.

All Publications

Multilayered nanofibrous-scaffold of Polyvinyl alcohol/gelatin/poly (lactic-co-glycolic acid) enriched with hemostatic/antibacterial agents for rapid acute hemostatic wound healing by Pandey G., Pandey P. , Arya D. K., Kanaujiya S. , Kapoor D. D., Gupta R. K., Ranjan S. , Chidambaram K. , Manickam B. , Rajinikanth P. International Journal of Pharmaceutics 638 122918- (2023)
ECM Mimicking Biodegradable Nanofibrous Scaffold Enriched with Curcumin/ZnO to Accelerate Diabetic Wound Healing via Multifunctional Bioactivity by Yadav S., Arya D.K., Pandey P., Anand S., Gautam A.K., Ranjan S., Saraf S.A., Rajamanickam V.M., Singh S., Chidambaram K., Alqahtani T., Rajinikanth P.S. International Journal of Nanomedicine 17 6843-6859 (2022)
Polyurethane Chemistry for the Agricultural Applications â Recent Advancement and Future Prospects by Ghosh A., Chowdhury S.R., Dutta R., Babu R., Rumbo C., Dasgupta N., Mukherjee P., Das N.C., Ranjan S. ACS Symposium Series 1454 1-36 (2023)
3D Printing in Biotechnology: Current Technologies and Applications by Dasgupta N., Singh V. , Ranjan S. , Mishra T. , Mishra B. 1-300 (2024)
Biotechnology for Toxicity Remediation and Environmental Sustainability by Gothandam K.M., Srinivasan R., Ranjan S., Dasgupta N. Biotechnology for Toxicity Remediation and Environmental Sustainability 1-283 (2023)

Completed Projects

Principal Investigator

3D Printed Bioresorbable Microneedle array- based sutureless breathable dermal- substitute system for second-degree burn wounds to treat microbial infection, hypertrophic scar, and with skin regenerative properties (3DBioResMiNee) INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
Developing Human Bone mimetic 3D Bio-printed Organoid Models for Drug / Toxicology Screening: Characterizing it with Advanced Imaging Scheme for Promotion of Academic and Research Collaboration (SPARC), Apex Committee of SPARC, Ministry of Education
Ligand functionalized nano-formulation for the targeted delivery of Everolimus in non-cancerous neuroendocrine tumours of pituitary, lung and pancreas SRIC, IIT KHARAGPUR
Nanoengineered 3D Printed Thinner BRS for Controlled Degradation, Efficient Endothelialization, Antithrombotic, and vSMC-Antiproliferative: An Indigenous Approach to Treat Atherosclerosis (3DNanoResStent) INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)

Co-Principal Investigator

FTIR Spectroscopic Study And Raman Study In Homoeopathic Potentized Medicines and Characterization, Standardization and Analysis of the Imponderable Medicines (X-Ray, Electricity, Magnetis Polus Australis etc.) Central Council for Research in Homoeopathy (CCRH)

Alumni members