Home > Academics > Academic Units > Schools > School of Medical Science and Technology > Gorachand Dutta
Assistant Professor Grade-I
School of Medical Science and Technology
Over the years, there are increasing needs for the development of simple, cost-effective, portable, integrated biosensors that can be operated outside the laboratory by untrained personnel. However, to reach this goal a reliable sensor technology based on printed electronics has to be developed. Our group aims to develop and establish the field of Biosensor and Electrochemistry for Bench to Bedside diagnosis. Our goal will be the use of redox cycling-based wash-free electrochemical technique in a portable electronic device that can be operated outside the laboratory for simple and effective point-or-care testing in India for early stage disease diagnosis (i.e. cancer, malaria, dengue, tuberculosis, HIV/AIDS etc.). The main challenges of point-of-care testing require to implement complex analytical methods into low-cost technologies. This is particularly true for countries with less developed health care infrastructure. Our washing-free technique is very simple and innovative. We can develop a low-cost disposable wash-free chip and our approach will make it possible to perform highly sensitive detection of biomarkers with printed electronics. The redox cycling technology will detect several interesting targets at the same time on a printed chip. The proposed research projects are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics & electrical engineering, healthcare and manufacturing, entailing close collaboration and knowledge exchange among the different labs.
Also our focused areas: (1) integration of biosensors with fuel cell for self-powered biodevices, (2) low-cost, fully integrated biosensor devices using Lab-on-Printed Circuit Board (PCB) approach, (3) enzyme based immunosensor (ELISA), (4) ultra-sensitive biosensors using magnetic bead assays, nanoparticles, CNT, dendrimer, (5) Lab-on-a-Chip devices for biomedical diagnostics, (6) bio-nanotechnology for drug delivery, (7) microfluidics.
Wash-free, label-free immunoassay for rapid electrochemical detection of PfHRP2 in whole blood samples by Dutta G., Lillehoj P. Scientific Reports, (ISSN: 2045-2322) 8 17129- (2018)
Enzyme-free electrochemical immunosensor based on methylene blue and the electro-oxidation of hydrazine on Pt nanoparticles by Dutta G., Nagarajan S. , Lapidus L. , Lillehoj P. Biosensors and Bioelectronics (ISSN: 0956-5663) 92 372-377 (2017)
Low-interference washing-free electrochemical immunosensor using glycerol-3-phosphate dehydrogenase as an enzyme label by Dutta G., Park S. , Singh A. , Seo J. , Kim S. , Yang H. Analytical Chemistry (ISSN: 0003-2700) 87 3574-3578 (2015)
Improvement of the electrocatalytic activities of long-aged Pt electrodes and the change of the improved activities with aging by Dutta G., Haque A. , Yang H. Electrochimica Acta (ISSN: 0013-4686) 141 319-323 (2014)
Washing-free heterogeneous immunosensor using proximity-dependent electron mediation between an enzyme label and an electrode by Dutta G., Kim S. , Park S. , Yang H. Analytical Chemistry (ISSN: 0003-2700) 86 4589-4595 (2014)
An ultrasensitive enzyme-free electrochemical immunosensor based on redox cycling amplification using methylene blue (This article is part of the themed collection) by Dutta G., Lillehoj P. Analyst (ISSN: 0003-2654) 3492-3499 (2017)
Time-dependent decrease in the enhanced electrocatalytic activities observed after three different pretreatments of gold electrodes by Dutta G., Jo K. , Lee H. , Kim B. , Woo H. , Yang H. Journal of Electroanalytical Chemistry (ISSN: 1572-6657) 675 41-46 (2012)
Effect of fenton's reagent on the electrocatalytic activity of gold nanoparticles by Dutta G., Yang H. Electrochemistry Communications (ISSN: 1388-2481) 13 1328-1331 (2011)
Redox cycling-amplified enzymatic Ag deposition and its application in highly sensitive detection of creatine kinase-MB by Haque A., Kim J. , Dutta G. , Kim S. , Yang H. Chemical Communication (ISSN: 1359-7345) 51 14493-14496 (2015)
Design of an Electrochemical Lab-on-a-Chip Biosensor Device for COVID-19 Diagnosis Human Biogenesis Private Limited
Electrochemical Printed Chip Device for Next Generation Point-of-Care Disease Detection ISIRD, SRIC
Srideep Maity
Area of Research: Medical Image processing
Riddhipratim Mandal
Area of Research: Biosensors
Nirmita Dutta
Area of Research: Biosensors for Point of care
Amlan Ashish
Area of Research: Biosensors for Point-of-Care
Suraj Mal
Area of Research: BIosensor
