IITKGP
Back to Concern Department

School of Medical Science and Technology

Faculty

Koel Chaudhury, IIT Kharagpur

Koel Chaudhury

Professor

School of Medical Science and Technology

+91-3222-283572

koel@smst.iitkgp.ac.in

Awards and Accolades

Personal Webpage Bio Sketch

Responsibilities

  • Advisor, Spring Fest
  • Presiding Officer, Internal Complaints Committee (ICC)

Research Areas

  • Non-invasive biomarkers and sensors
  • Women's health
  • Respiratory disorders
  • Metabolomics
The Clinical Biomarkers Discovery Laboratory is actively involved in using the newly emerged field of metabolomics, which is capable of providing biological end-point markers of the cellular processes that occur as a result of disease. Metabolomics has rapidly evolved during the recent years and is complementary to different ‘omics’ technologies, such as transcriptomics and proteomics. We focus on the use of metabolomics for comprehensive identification of disease biomarkers and understanding of the pathogenic mechanism underlying complex human diseases. We have extensively used the metabolomics approach to investigate Women’s health with an emphasis on pregnancy-related complications. Early-stage biomarkers specific to Stage I and Stage II endometriosis have been successfully identified and validated. Design of a biochemical sensor based on these findings is underway. Biomarkers for gestational hypertension, recurrent miscarriage, polycystic ovarian syndrome (PCOS) and female dormant genital tuberculosis are also being explored. Recently, our team has initiated work in the area of Respiratory health. We are using metabolomics for the identification of unique metabolic fingerprints in exhaled breath condensates and serum for differentiating the various endotypes/sub-types of asthma and chronic obstructive pulmonary disease (COPD). Dyregulated glucose and lipid metabolism intermediates and amino acid changes between the sub-types have been identified. We are also profiling other respiratory disorders including interstitial lung disease (ILD), pulmonary hypertension and lung cancer with an aim to enhance the scope for novel point of care device development. 
All Publications
    No Record Found.
Completed Projects

Principal Investigator

  • Analysis of Gut Microbiome and Metabolome in Women with Polycystic Ovary Syndrome DBT, NEW DELHI
  • Integrated transcriptomics, metabolomics and microbiome signatures-based prediction ofCOPD patients at-risk of progressing to lung cancer INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Integration of metabolome, transcriptome and microbiome data to differentiate between chronic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis Science and Engineering Research Board (SERB)
  • Integration of metabolome, transcriptome and microbiome data to differentiate between chronic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis Anusandhan National Research Foundation (ANRF)
  • Lipid profiling and spatial lipid mapping of the endometrium in recurrent pregnancy loss using LC-MS and DESI imaging INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Multi-omics integrated machine learning approach for prediction of women at-risk of undergoing recurrent implantation failure (RIF) INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Next-Generation Single-Sheet Lateral Flow-Electrochemical Device Rapid Detection of Neurofilament Light Chain in Neurdegenerative Disease Diagnosis Anusandhan National Research Foundation (ANRF)
  • SMST Facility User Charges for External User Various Sponsors

Co-Principal Investigator

  • Artificial Intelligence Assisted Ultrasound-guided Surgery of Non-palpable Breast Cancer and Therapy (AASTHA) INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Artificial Intelligence augmented oocyte retrieval for improved outcome of Assisted Reproductive Technologies (Al4ART) IIT KHARAGPUR AI4ICPS I HUB FOUNDATION
  • DEVELOPMENT OF A PAPER BASED IMPEDIMETRIC SENSOR FOR RAPID AND QUANTITATIVE ASSESSMENT OF pH, UREA AND CREATININE IN BLOOD INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Differential expression of Follicular fluid Fatty acids in women with polycystic ovaries: correlation with successful pregnancy outcome INDIAN COUNCIL OF MEDICAL RESEARCH (ICMR)
  • Final Validation, Marketing and Dissemination of Developed Electrochemical LabelFree Biosensing Device Rheumotron Moby for the Detection of Multiple Rheumatoid Arthritis Biomarkers Rheumatoid Factor, AntiCyclic Citrullinated Peptide Antibody and CReactive Protein Indian Council of Medical Research (ICMR)
Alumni members

Ph. D. Students

Anindita Bhattacharya

Area of Research: Lung cancer pathogenesis

Bishnupriya Saha

Area of Research: Women''s health

Imon Mitra

Area of Research: Women''s reproductive health

Palash Paul

Area of Research: Interstitial lung diseases and omics

Pragya Dey

Area of Research: Lung cancer and COPD

Sayak Roy Chowdhury

Area of Research: Nanomaterials application in Biotechnology

Shreya Choudhury

Area of Research: Aptamer Based Biosensors

Soumendranath Ray

Area of Research: Thyroid cancer

Sumana Halder

Area of Research: Multimodal Imaging for precision dosimetry