Indian Institute of Technology Kharagpur |

DAAD Research Ambassador
Young Associates of Maharashtra Academy of Sciences
Ph.D. Guideship Recognition
DST-INSPIRE Faculty Award
Max-Planck Postdoc Fellowship

Journal

Enhancing RNAi activity through 4 -O-hexadecyl-2 -deoxythymidine modification in the passenger Strand by Gangopadhyay S., Gore K. R. Bioorganic & Medicinal Chemistry 137 118614-118620 (2026)
Modulating p?? Conjugation with Hybridized Local and Charge-Transfer Excited-State Manifolds: Toward Bimodal Photocatalysts for Efficient Energy and Electron Transfer Catalysis by Shee M., Das G., Chatterjee S., Layek S., Gore K.R., Singh N.D.P. ACS Catalysis 15 18204-18217 (2025)
Modulating p- conjugation with Hybridized Local and Charge-Transfer Excited-State Manifolds: Towards Bimodal Photocatalysts for Efficient Energy and Electron Transfer Catalysis. by Shee M., Das G. , Chatterjee S. , Layek S. , Gore K. R., Pradeep N. D. ACS Catal. 15 18204-18217 (2025)
Investigation of 4-Nitro-N, N-diphenylaniline as a chemical tracer under high pressure high temperature reservoir conditions for enhanced oil recovery applications by Maiti S., Choudhary N. K., Gore K. R., Kulkarni S. D. Journal of Petroleum Exploration and Production Technology 15 1-28 (2025)
Investigation of 4-Nitro-N, N-diphenylaniline as a chemical tracer under high pressure high temperature reservoir conditions for enhanced oil recovery applications by Maiti S., Choudhary N.K., Gore K.R., Kulkarni S.D. Journal of Petroleum Exploration and Production Technology 15 - (2025)
Exploring Excited-State Intramolecular Proton-Coupled Electron Transfer in Dinuclear Ir(III)-Complex via Covalently Tagged Hydroquinone: Phototherapy Through Futile Redox Cycling by Shee M., Schleisiek J., Maity N., Das G., Montesdeoca N., Ha-Thi M.-H., Gore K.R., Karges J., Singh N.D.P. Small 21 - (2025)
4?-C-Cholesterol/Pyridyl-2?-O-Methyl Uridine-Functionalized siRNA Enhances Stability and Carrier-Free Gene Silencing by Sar S., Gupta S., Das G., Sharma S.N., Deepak K., Ghosh A., Bagale S.S., Gangopadhyay S., Sinha S., Gore K.R. Bioconjugate Chemistry 36 1234-1246 (2025)
4?-O-methoxyethyl-2?-deoxy-uridine and cytidine ribonucleotides improve duplex stability, nuclease resistance, and elicit efficient knockdown of Bcl-2 expression by Gangopadhyay S., Das G., Sharma S.N., Ghosh A., Bagale S.S., Sinha S., Gore K.R. Bioorganic and Medicinal Chemistry Letters 128 - (2025)
Enhanced G-Quadruplex Stability and Anticancer Activity of N2-Aryl Deoxyguanosine-Modified T40214 Oligonucleotides Targeting STAT3 in Prostate Cancer by Choudhary N.K., Sharma S.N., Das G., Ghosh A., Bagale S.S., Sinha S., Gore K.R. Biochemistry 64 3203-3218 (2025)
Thermodynamic Destabilization and Structural Adaptability of 2?-Alkoxy/Fluoro-N3-Methyl Pyrimidine Nucleotides in siRNA Enhance RNA Interference Activity by Sahoo A., Gupta S., Das G., Sharma S.N., Ghosh A., Bagale S.S., Sinha S., Gore K.R. Journal of Medicinal Chemistry 68 16371-16394 (2025)
N3-Methyluridine and 2â ²-O-Alkyl/2â ²-Fluoro-N3-methyluridine functionalized nucleic acids improve nuclease resistance while maintaining duplex geometry by Sahoo A., Das G., Ghosh A., Shivappa Bagale S., Kumar Choudhary N., Harikrishna S., Sinha S., Gore K.R. Bioorganic and Medicinal Chemistry 100 - (2024)
Selective Recognition of the Dimeric NG16 Parallel G-Quadruplex Structure Using Synthetic Turn-On Red Fluorescent Protein Chromophore by Choudhary N.K., Gupta S., Das G., Sahoo A., Harikrishna S., Sinha S., Gore K.R. Biochemistry 63 2842-2854 (2024)
Synthesis of N3-Methyluridine- and 2 -O-Alkyl/2 -Fluoro-N3-Methyluridine-Modified Phosphoramidites and Their Incorporation into DNA and RNA Oligonucleotides by Sahoo A., Gore K.R. Current Protocols 4 - (2024)
2 -O-Alkyl-N3-Methyluridine Functionalized Passenger Strand Improves RNAi Activity by Modulating the Thermal Stability by Sahoo A., Gupta S., Das G., Ghosh A., Bagale S.S., Sinha S., Gore K.R. ACS Medicinal Chemistry Letters 15 1250-1259 (2024)
4â ²-C-Acetamidomethyl-2â ²-O-methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small Interfering RNAs by Gangopadhyay S., Das G., Gupta S., Ghosh A., Bagale S.S., Roy P.K., Mandal M., Harikrishna S., Sinha S., Gore K.R. Journal of Organic Chemistry 89 3747-3768 (2024)
Investigating the Effect of Chemical Modifications on the Ribose Sugar Conformation, Watson-Crick Base Pairing, and Intrastrand Stacking Interactions: A Theoretical Approach by Das G., Harikrishna S., Gore K.R. Journal of Physical Chemistry B 128 8313-8331 (2024)
Exploring Excited-State Intramolecular Proton-Coupled Electron Transfer in Dinuclear Ir(III)-Complex via Covalently Tagged Hydroquinone: Phototherapy Through Futile Redox Cycling by Shee M., Schleisiek J., Maity N., Das G., Montesdeoca N., Ha-Thi M.-H., Gore K.R., Karges J., Singh N.D.P. Small 20 24084- (2024)
Vinyl substituted triphenylamine based turn-off fluorescent probe for selective and sensitive detection of mercury (II) in water and live cells by Choudhary N.K., Mittapelli L.L., Kumar Roy P., Das G., Mandal M., Gore K.R. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 285 - (2023)
Advances in siRNA Therapeutics and Exploring Synergistic Effect of Emerging Dual Modifications in Sugar on siRNA Activity by Gore K. R., Gangopdhyay S. RNA Biology 19 452-467 (2022)
Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications by Gangopadhyay S., Gore K.R. RNA Biology 19 452-467 (2022)
Stereochemistry: A three dimensional insight. By Anil V. Karnik and Mohammed Hasan, Elsevier, 2021. 594 pp., paperback $225. ISBN 978 0 12 821062 8 by Gore K. R., Patwari A. Chirality 34 1538-1539 (2022)
Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review by Das G., Harikrishna S., Gore K.R. Chemical Record 22 - (2022)
Understanding effect of fluid salinity on polymeric drag reduction in turbulent flows of slickwater fluids by Korlepara N. ., Patel N. , Dilley C. , Deysarkar A. K., Gore K. R., Kulkarni S. D. Journal of Petroleum Science and Engineering 216 1-10 (2022)
Folate Receptor-Mediated siRNA Delivery: Recent Developments and Future Directions for RNAi Therapeutics by Gangopadhyay S., Nikam R.R., Gore K.R. Nucleic Acid Therapeutics 31 245-270 (2021)
Folate Receptor-Mediated siRNA Delivery: Recent Developments and Future Directions for RNAi Therapeutics by Gore K. R., Gangopadhyay S. , Nikam R. R. Nucleic acid Therapeutics 1 - (2021)
Synthesis, Structural, and Conformational Analysis of 4 -C-Alkyl-2 -O-Ethyl-Uridine Modified Nucleosides by Nikam R.R., Harikrishna S., Gore K.R. European Journal of Organic Chemistry 2021 924-932 (2021)
LiHMDS: Facile, Highly Efficient, and Metal-Free Transesterification under Solvent-Free Condition by Gore K. R., Mittapelli L. L. Catalysis Communications 149 106194-106199 (2021)
A mild and convenient approach for selective acetonide cleavage involved in carbohydrate synthesis using PPA-SiO2 by Nikam R.R., Gore K.R. Journal of Carbohydrate Chemistry 39 63-74 (2020)
A mild and convenient approach for selective acetonide cleavage involved in carbohydrate synthesis using PPA-SiO2. by Nikam R. R., Gore K. R. Journal of Carbohydrate Chemistry; Corresponding author, Research paper affiliated to IIT Kharagpur) 39 63-74 (2020)
LiHMDS: Facile, highly efficient and metal-free transesterification under solvent-free condition by Mittapelli L. L., Gore K. R. Catalysis Communications 149 106194-106199 (2020)
A Novel Green Florescent Protein Analog for Selective and Rapid Detection of H2S in Water as well as in Living Cells by Mittapelli L. L., Nawale G. N., Gholap S. P., Varghese O. P., Gore K. R. Sensors and actuators B: Chemical 298 126875-126882 (2019)
large Stokes shift fluorogen-activating RNA aptamer by Steinmetzger C., Palaniswamy N. , Gore K. R., Höbartner C. Chemistry-European Journal 25 1931-1935 (2019)
Journey of siRNA: Clinical Developments and Targeted Delivery by Nikam R. R., Gore K. R. Nucleic Acid Therapeutics 1 209-224 (2018)
Novel Silylated HBI Analog for Rapid, Selective, and Sensitive Detection of Cyanide in Water and Living Cells by Mirajkar A. L., Mittapelli L. L., Nawale G. N., Gore K. R. Sensors and actuators B: Chemical 265 257-263 (2018)
The N2-Furfural Deoxyguanosine (fdG) Adduct Does Not Alters The Structure of B-DNA by Ghodke P., Gore K. R., Harikrishna S. , Samanta B. , Kottur J. , Nair D. T., Pradeepkumar P. I. Journal of Organic Chemistry 81 502-511 (2016)
Unique Structural Features in DNA polymerase IV Enable Efficient Bypass of the N2 Adduct Induced by the Nitrofurazone Antibiotic by Kottur J., Sharma A. , Gore K. R., Narayan N. , Samanta B. , Pradeepkumar P. I., Nair D. T. Structure 23 56-67 (2015)
Influence of 2 -Fluoro versus 2 -O-Methyl Substituent on the Sugar Puckering of 4 -C-Aminomethyl-uridine by Gore K. R., Harikrishna S. , Pradeepkumar P. I. Journal of Organic Chemistry 78 9956-9962 (2013)
Design, Synthesis, Biophysical and Primer Extension Studies of Novel Acyclic Butyl Nucleic Acid (BuNA) by Kumar V., Gore K. R., Pradeepkumar P. I., Kesavan V. Organic and Biomolecular Chemistry 11 5853-5865 (2013)
Synthesis, Gene Silencing, and Molecular Modelling Studies of 4 -C-Aminomethyl-2 -O-Methyl-Modified Small Interfering RNAs by Gore K. R., Nawale G. N., Harikrishna S. , Chittoor V. , Pandey S. , Höbartner C. , Patankar S. , Pradeepkumar P. I. Journal of Organic Chemistry 77 3233-3245 (2012)
Incorporation of 4'-C-Aminomethyl-2'-O-Methylthymidine into DNA by Thermophilic DNA Polymerases by Nawale G. N., Gore K. R., Höbartner C. , Pradeepkumar P. I. Chemical Communications 48 9619-9621 (2012)

Patent

4 -O-methoxyethyl 2 -deoxyuridine and 2 -deoxycytidine Modified Phosphoramidite Building Blocks and its Incorporation into Small Interfering RNAs by Gore K. R., Gangopadhyay S. - (2024)
Distinguishing Fluoride and Cyanide Using Turn-On Fluorescent Chemodosimeter Based Upon Synthetic GFP Chromophore Analog in Polar Protic Solvent. Gore, K. R.; Mittapelli, L.L.; Nawale, G. N. (Patent application published dated 28/02/2020, Application number 201821031531). by Gore K. R., Mittapelli L. L., Nawale G. N. - (2020)
Highly Selective Detection and Discrimination of H2S over Cysteine Based Upon Novel Acryloyl GFP Chromophore Analog. Gore, K. R.; Mittapelli, L. L.; Nawale, G. N. (Patent application published dated 28/02/2020, Application number 201821031530). by Gore K. R., Mittapelli L. L., Nawale G. N. - (2020)
Novel Silylated HBI Analog for Rapid, Selective, and Sensitive Detection of Cyanide in Water and Living Cells. Gore, K. R.; Mittapelli, L.L.; Mirajkar, A. L.; Nawale, G. N. (Patent under examination dated 30/01/2020, Application number 201821004548). by Gore K. R., Mittapelli L. L., Mirajkar A. L., Nawale G. N. - (2020)
Synthesis of N2-Furfuryl Deoxyguanosine Phosphoramidite and Modified Oligonucleotides, Gore, K. R.; Nair, D. T.; Pradeepkumar, P. I. (Granted, Patent Number 295309). by Gore K. R., Nair D. T., Pradeepkumar P. I. - (2018)

Conferences

Microwave Assisted Selective Acetonide Cleavage Involved in Multi-Step Sugar Synthesis: A Greener Approach Over Conventional Synthetic Route by Nikam R. R., Chavan A. R., Gore K. R. RECENT TRENDS IN CHEMICAL AND PHYSICAL SCIENCES 58-62 (2019)
Towards elucidation of catalytic DNA: an EPR spectroscopic approach on copper (Cu2+) binding site by Sicoli G., Gore K. R., Hoebartner C. , Mouesca J. M., Gambrelli S. European Biophysics Journal; https://doi.org/10.1007/s00249-015-1045-6 43-248 (2015)