Welcome to the Multiphysics Simulation Group at IIT Kharagpur. Our research operates at the intersection of numerical methods, applied mechanics, thermodynamics and bioprocess engineering. We specialize in developing high-fidelity numerical frameworks to understand complex phenomena, with a particular interest in applications such as delivery systems for next-generation therapeutics and hydrodynamic cavitation. Our mission is to bridge fundamental physics with scalable engineering solutions to address challenges in healthcare, advanced manufacturing and energy.
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Phase-field modeling for flow simulation by Gomez H., Leng Y. , Hu T. , Mukherjee S. , Calo V. Frontiers in Computational Fluid-Structure Interaction and Flow Simulation: Research from Lead Investigators Under Forty-2023 79-117 (2023)
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Understanding how non-condensable gases modify cavitation mass transfer through the van der Waals theory of capillarity by Mukherjee S., Gomez H. Applied Physics Letters 117 - (2020)
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Simulating surfactant effects in phase-transforming fluids by Feng K., Mukherjee S. , Hu T. , Gomez H. Physics of Fluids 38 - (2026)
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Understanding Size Distributions during Lipid Nanoparticle Manufacturing through Mechanistic Modeling by Mukherjee S., Shin S. , Devos C. , Udepurkar A. , Sagmeister . , Trout B. L., Myerson A. S., Braatz R. D. ACS Omega 11 26901-26908 (2026)
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Hydrodynamic cavitation with non-condensable gases: A thickened interface method with differentiable non-equilibrium thermodynamics based on van der Waals theory by Mukherjee S., Gomez H. Journal of Computational Physics 536 114070- (2025)
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Impinging jet mixers: A review of their mixing characteristics, performance considerations, and applications by Devos C., Mukherjee S. , Inguva P. , Singh S. , Wei Y. , Mondal S. , Yu H. , Barbastathis G. , Stelzer T. , Braatz R. , Myerson A. AIChE Journal 71 - (2025)
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Mechanistic modeling of lipid nanoparticle formation for the delivery of nucleic acid therapeutics by Inguva P., Mukherjee S. , Walker P. , Tenberg V. , Devos C. , Shin S. , Wu Y. , Santra S. , Wang J. , Singh S. , Kanso M. , Kim S. H., Trout B. , Bazant M. , Myerson A. , Braatz R. Biotechnology Advances - (2025)
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Mixtures of phase transforming fluids and gases: Phase field model and stabilized isogeometric discretization by Mukherjee S., Gomez H. Computers & Fluids 271 106176- (2024)
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Stabilized formulation for phase-transforming flows with special emphasis on cavitation inception by Mukherjee S., Gomez H. Computer Methods in Applied Mechanics and Engineering 415 116228- (2023)
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Effect of dissolved gas on the tensile strength of water by Mukherjee S., Gomez H. Physics of Fluids 34 - (2022)
- Co-Principal Investigator
Ph. D. Students
Ramendranath Halder
Area of Research: Microfluidic transport
